Anthropology: Artifacts from the Lower Pecos Texas Region as well as American Indian, pre-Columbian, and Filipino artifacts.
Art: Texas paintings, folk art, furniture, and decorative arts, as well as
American furniture and decorative arts.
History: Artifacts from the American West, general store items, and weapon collection.
Natural History: Gems, minerals, herpetology, paleontology, ornithology, and entomology.
Textiles: American fashions primarily from the 19th century to the present, Chinese and Japanese costumes, Filipino costumes and textiles, European and Meso-American folk costumes, quilts and coverlets, pageant costumes from San Antonio Fiesta.