As an American art and regional history museum, and the second largest general museum in Georgia, the Columbus Museum offers a diverse collection to the public. The Museum houses over 14,000 artifacts and objects that tell the story of the Chattahoochee River Valley's development, an American fine art collection from a host of renowned American artists, a hands-on gallery for children, and the finest traveling exhibitions from across the U.S. In addition, the Museum also features a range of educational programming for adults, families, and children. The Museum is always changing and always free, so come back again and again to experience award-winning collections and new and exciting programs.

The mission of the Columbus Museum is to collect, preserve, research and interpret American art and regional history for the education, enrichment and enjoyment of a broad and diverse public.